Letrozole For Infertility
Letrozole is an oral medication that can help facilitate effective fertility treatment for ladies with ovulation concerns.
The drug is under the classification of aromatase inhibitors. Letrozole is mainly assimilated to treat women with ovulation problems and people with unexplained infertility.
The medication is in the class of drugs called aromatase inhibitors. The letrozole has majorly been used to help treat medical cases connected to cancer.
How Letrozole Induce Ovulation
When it’s orally ingested the enzyme aromatase is inhibited by the letrozole medication and estrogen levels are inhibited in young women. Thus, the brain and pituitary gland increase the output of FSH (follicle stimulating hormone).
When it comes to women, pol,ycystic ovary syndrome (which is a problem with ovulation) increases in FSH hormone, which results in the growth of mature follicles in the ovary and the ovulation of eggs. Therefore, doctors call this process induction of ovulation.
In women who ovulate on their own, the treatment with Letrozole can result in the growth of multiple follicles and multiple egg releases. Hence, the release of multiple eggs causes an increased rate of pregnancy compared to the release of one egg with a natural menstrual cycle.
The release of multiple eggs through simulation ovulation of multiple follicles and eggs is referred to as superovulation or ovarian hyperstimulation.
The Chances of Ovulation With the Use of Letrozole
With the assimilation of the medication, there is an increased 15 percent chance of getting pregnant. The Letrozole is mainly used when:
There is higher success for women not ovulating on their level.
The female partner is under 35 years old.
There is lower success for unexplained fertility in ovulating women.
Dosing
The most common dose of Letrozole is 2.5 mg per day on days five through nine of the menstrual cycle. Moreover, sometimes it is given in more doses of 5 mg or 7.5 mg per day.
Risks and Side Effects
A person using the medication has higher rates if birth defects.
There is a risk of twins with the use of Letrozole.
Headaches.
Stomach upset.
Weakness and back pain.
Pain during sexual intercourse.
PHOTO CREDIT:GOOGLE.COM
WRITTTEN BY:AMEDDIC.COM